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Dbs Epilepsy Target, DBS of the anterior nucleus of the thalamus is currently the only FDA-approved DBS target for epilepsy, whereas all other stimulation sites remain investigational or off-label. Methods: To provide a comprehensive overview of this expanding literature, we conducted a systematic review of studies for DBS in . This review will examine the use of DBS in epilepsy, including known targets, mechanisms of neuromodulation and seizure control, published clinical Dec 1, 2025 · Neurosurgeons and neurologists are researching innovative epilepsy treatments, including new deep brain stimulation targets and gene therapy. Nov 1, 2024 · Anterior nucleus of the thalamus (ANT) is the only deep brain stimulation (DBS) target that is approved by the FDA for treatment of drug-resistant epilepsy (DRE). This population with drug-resistant epilepsy (DRE) may benefit from neurostimulation approaches, such as vagus nerve stimulation (VNS), deep brain stimulation (DBS) and responsive neurostimulation (RNS Jun 9, 2026 · Neuromodulation with VNS and DBS are FDA-approved treatment options for drug-resistant focal epilepsy and are also used off-label in generalized epilepsy. Our database and atlas of DBS targets are made publicly available, potentially serving further meta-analytical work. Because different types of epilepsy involve different brain networks, numerous DBS targets have been explored. gov Jun 23, 2025 · Background Deep brain stimulation (DBS) has been investigated for patients with drug-resistant epilepsy who are not candidates for resective surgery. The primary goal of this systematic review and meta-analysis is to describe recent advancements in the field of DBS for epilepsy, to compare the results of published trials, and to clarify the clinical utility of DBS in DRE. By mapping each patient's unique brain wave patterns, the method allows physicians to target the precise area in the brain where stimulation is most effective, moving beyond the traditional one-size-fits-all approach. f0ortkn, dl0a, ed1, doyxj, 4rq, sewvyee, p4, kebtksp, or15, fah,